Novel Insecticides from Alkylated and Acylated Derivatives of Thymol and Eugenol for the Control of Plutella xylostella (Lepidoptera: Plutellidae)

Plutella xylostella cause considerable harm to the production of broccoli, Chinese cabbage, cabbage and cauliflower. The control P. is mainly performed using commercial insecticides, which have even led emergence resistant populations. Two easily available natural products found in different plants essential oil, thymol eugenol, stand up as possible novel agents this pest. In work a series alkylated acylated derivatives eugenol were synthesized screened for antifeedant, larvicidal ovicidal activities against xylostella. results biological assays suggest that 1,1’-[1,8-octanediylbis(oxy)]-bis(4-allyl-2-methoxy-benzene) (5) was most toxic test. Compounds 1-butoxy-2-isopropyl-5-methyl-benzene (8) hexanedioic acid 1,6-bis(2-isopropyl-5-methyl-phenyl)-ester (10) assay. compound 8 presented antifeedant activity. Most compounds obtained more active than commercially insecticidal deltamethrin azadirachtin.